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| from = trazodone
| to = vortioxetine
| stop = * '''Before day 1:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day. * '''Day 1:''' reduce the dosage of trazodone to 75-100 mg/day.* '''Day 8:''' when a dosage of 75 mg/day is reached{{StopSSRI, stop administrationSNRI}}| start = {{StartAntidepressant}}* A wash-out period is not necessary.| info =* '''Day 8:''' start administration of Safe target dose vortioxetine in a normal dosage of = 10 mg/day.| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.{{reviewtheorSS}}
}}
