Bureaucrats, checkuser, developer, editor, reviewer, Administrators, widgeteditor
1,951
edits
Changes
no edit summary
{{Drug
| name = valproic Valproic acid
| group = anticonvulsant
| type = Moodstabilizermoodstabilizer
| wikipedia = valproic_acid
| medscape = 8885
| pubchem = 3121
| drugscom = valproic-acid-and-derivatives-divalproex-sodium-sodium-valproate
| drugscomid = valproic-acid
| ftk = valproinezuur
| ATC = N03AG01
| metabolization = * Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.| metabolization_ref = <ref name="ftk">{{FTK|valproinezuur}}</ref>| administration = OralO, rectalR
| ctox = 150000
| ctox_ref = <ref name="ftktox">{{ftktox}}</ref>
| cth = 50000-100000
| halflife = 10-15
| halflife_ref = <ref name="ftk">{{FTK|valproinezuur}}</ref>
| metabolites bioavailability = 1100| metabolites_ref bioavailability_ref = <ref name="ftkinformatorium" >{{KNMP|valproaat}}</ref>| <includeonly>| isswitch = 1</includeonly>
}}
