| to = amitriptyline
| stop =
* '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.* '''Day 1:''' reduce a dosage of 75 mg/day to 37,5 mg/day.* '''Day 8:''' stop administration of venlafaxine. {{TCAdecrease25p3d}}
| start =
* '''Day 1:''' simultaneously start administration of amitriptyline in a low dosage of 25 mg/day. * '''Day 8:''' continue administration of amitriptyline in a dosage of 50 mg/day.{{TCAincrease25p3d}}| info = * “Start low, go slow” for amitriptyline, and caution with this switch is necessary. {{TCAplasmalevelmonitoring}}* Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes amitriptyline.}}
