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Venlafaxine-hypericum

361 bytes removed, 12:44, 4 November 2015
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| to = hypericum
| stop =
* '''Before day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/day, when this dosage is > 75 mg/day. * '''Day 1:''' reduce dosage of venlafaxine to 37,5 mg/day.* '''Day 8:''' stop administration of venlafaxine.{{stopVenlafaxine}}
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* '''Day 8-1415:''' a wash-out period of one week is necessary.* '''Day 1516:''' start administration of hypericum in a dosage of 300 mg three times a day (900 mg/day).
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.| caveat = {{caveSS}}| info ={{HypericumInfo}} * Hypericum slows the metabolism of venlafaxine via CYP3A4. }}
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