| to = citalopram
| stop =
* '''Day 1:''' reduce dosage of vortioxetine to 5 mg/day.* '''Day 7:''' stop administration of vortioxetine.{{stopVortioxetine}}
| start =
* No wash-out period is needed.
* '''Day 89:''' Start citalopram in a normal dosage of 20 mg/day.
| info =
* {{theorSS}}<ref>[http://www.ema.europa.eu/docs/nl_NL/document_library/EPAR_-_Product_Information/human/002717/WC500159449.pdf European Medicines Agency. SmPC Brintellix 5 mg.]</ref>
* because of halflifes of both compunds, there will be automatic crosstapering in the body{{AutomaticCrosstapering}}<ref name="vortiswitch"> {{Pubmed|24570588 |Katona et al.New generation multi-modal antidepressants: focus on vortioxetine for major depressive disorder. 2014 2014 Feb 19;10:349-54}}</ref> <ref name="informatorium">{{KNMP|vortioxetine}}</ref>
}}
