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| from = vortioxetine
| to = duloxetine
| stop = * '''Day 1:''' reduce dosage of vortioxetine to 5 mg/day.* '''Day 7:''' stop administration of vortioxetine.{{StopSSRI,SNRI}}| start = {{StartAntidepressant}}* '''Day 8:''' simultaneously start administration of duloxetine in a low dosage of 30 mg/day.| info =* '''Day 15:''' increase the dosage of Safe target dose duloxetine to = 60 mg/day.| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.{{theorSS}}* Duloxetine is a inhibitor of CYP2D6, which metabolizes vortioxetine.}}
