[[File{{Drugswitch | from = vortioxetine | to = fluoxetine| stop = {{stopVortioxetine}}| start = * A wash-out period of 2 weeks is necessary, because of CYP2D6-inhibition.* '''Day 23:''' start administration of fluoxetine in a normal dosage of 20 mg/day.| info = * {{theorSS}}* Fluoxetine is a strong inhibitor of CYP2D6, which metabolizes vortioxetine. <ref name="vortiswitch"> {{Pubmed|24570588 |Katona et al. New generation multi-modal antidepressants:Emptyfocus on vortioxetine for major depressive disorder.jpg]]2014 2014 Feb 19;10:349-54}}</ref> <ref name="informatorium">{{KNMP|vortioxetine}}</ref> }}
