Adding lamotrigine to aripiprazole.
- Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
- Lamotrigine is principally metabolised by UDP-glucuronosyltransferases.
- This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. 
- Start lamotrigine according to the general dosing advice.
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