Haloperidol LA-Partial agonist

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Haloperidol
long acting
Type Antipsychotic
Group Butyrophenones
links
ATC-code N05AD01
Medscape Haloperidol
PubChem 3559
PubMed Haloperidol
Drugs.com haloperidol
Kompas (Dutch) Haloperidol
Wikipedia Haloperidol
Partial agonists

Aripiprazole
Brexpiprazole
Cariprazine

Switch medication from Haloperidol_LA to Partial agonist.[4] [5]
Partial agonist is a collection of antipsychotic drugs having similar properties with respect to switching. A switch to member of the 'partial agonist' group from anotherdrug should be read as partial agonist-anotherdrug. Similarly, a switch from a member of the 'partial agonist' group to anotherdrug should be read as anotherdrug-partial agonist.

Nietinrijdenbord.png Stop Haloperidol_LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Partial agonist
  • Start drug at target dose on the day you would normally have injected the next depot.
Infobord.png More information
  • During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
  • There is a possibility of QT interval prolongation.[6]
    StopDepotStartArip.jpg
Nietinrijdenbord.png — Haloperidol_LA
Eenrichtingbord.png — Partial agonist


  1. WHO Collaborating Centre for Drug Statistics Methodology ATC=N05AD01
  2. 2.0 2.1 The Lundbeck Institute; Psychotropics; Terminal Plasma Half-lives
  3. 3.0 3.1 Farmacotherapeutisch Kompas; Inleidende Tekst Antipsychotica (dutch)
  4. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  5. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  6. Stöllberger C, Huber JO, Finsterer J, Antipsychotic drugs and QT prolongation. Int Clin Psychopharmacol. 2005 Sep;20(5):243-51.
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