Paliperidone SP-Paliperidone LP
From Psychiatrienet
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Switch medication from Paliperidone_SP to Paliperidone_LP.[1] [2]
Stop Paliperidone_SP - Day 1: Last depot injection
Start Paliperidone_LPStart depot on the day you would normally have injected the next depot. Determine the dose of paliperidone LP (Xeplion ®) by dividing the dose of paliperidone SP (Trivecta ®) by 3,5. Administer monthly. Loading dose is not needed[3]
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
- ↑ Switches are based on information of the KNMP Informatorium medicamentorum: Paliperidone, accessibele at https://www.kennisbank.knmp.nl
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