Paliperidone SP-Paliperidone UP

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Paliperidone SP
Trevicta® = super long acting, 90 days
Type Antipsychotic
Group Atypical AP
links
PubChem 23724979
PubMed SP%22 Paliperidone SP
Kompas (Dutch) Paliperidone SP
Wikipedia Paliperidone SP
Paliperidone UP
Byannli® = ultra long acting, 178 days
Type Antipsychotic
Group Atypical AP
links
PubChem 23724979
PubMed UP%22 Paliperidone UP
Kompas (Dutch) Paliperidone UP
Wikipedia Paliperidone UP

Switch medication from Paliperidone_SP to Paliperidone_UP.[1] [2]

Nietinrijdenbord.png Stop Paliperidone_SP
  • Day 1: Last depot injection
Eenrichtingbord.png Start Paliperidone_UP

Start depot on the day you would normally have injected the next depot. Determine the dose of paliperidone UP (Byannli ®) by multiplying the dose of paliperidone SP (Trivecta ®) 2 times . Administer every 6 months. [3]


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. Switches are based on information of the KNMP Informatorium medicamentorum: Paliperidone, accessibele at https://www.kennisbank.knmp.nl
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