Switch medication from Partial agonist to Chlorpromazine.
Partial agonist is a collection of antipsychotic drugs having similar properties with respect to switching. A switch to member of the 'partial agonist' group from anotherdrug should be read as partial agonist-anotherdrug. Similarly, a switch from a member of the 'partial agonist' group to anotherdrug should be read as anotherdrug-partial agonist.
Stop Partial agonist
- Day 1-21: Continue drug at usual dose
- Day 22: Stop drug
- Day 1-4: approx. 25% of target dose
- Day 5-8: approx. 50% of target dose
- Day 9-12: approx. 75% of target dose
- Day 13: target dose
- Day 28: Reevaluate dose, if necessary adjust dose
- During this switch you could monitor ECG, especially in patients prone to QT-conduction problems.
- There is a possibility of QT interval prolongation.
- During this switch monitoring of the haematological parameters is necessary.
— Partial agonist — Chlorpromazine
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