* '''Day 1:''' simultaneously start administration of bupropion is in a normal dosage of 150 mg/day. * '''Day 8:''' stop paroxetine and continue administration of if necessary increase bupropion in a dosage of 150 to 300 mg/day.| info =* '''Day 28:''' if necessary increase Its possible to start bupropion before day 1, while reducing the dose of paroxetine to 300 mg20mg/day.* Bupropion is a strong CYP2D6 inhibitor