* '''Day 3:''' reduce dosage of imipramine to 25 mg/day.
| start =
* '''Day 14:''' simultaneously start administration of paroxetine in a normal dosage of 20 mg/day.
* '''Day 8:''' stop administration of imipramine and continue administration of paroxetine.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Paroxetine is a strong inhibitor of CYP2D6, which metabolizes imipramine. }}