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* A wash-out period is not necessary.
* Start administration of mianserine the next day in a dosage of 30 mg/day.
* If necessary, increase dosage of mianserine to 40 mg/day.<ref name="agoswitch"> {{Pubmed|20196187|McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102}}</ref>}}
