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Created page with '{{Drugswitch | from = duloxetine | to = doxepin | stop = * '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day. * '...'
{{Drugswitch
| from = duloxetine
| to = doxepin
| stop =
* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day.
* '''Day 1:''' reduce dosage of duloxetine to a maximum of 30 mg/day.
| start =
A wash-out period of one week is necessary.
* '''Day 1:''' simultaneously start administration of doxepin in a low dosage of 25 mg/day.
* Day 8:''' stop administration of duloxetine and increase the dosage of doxepin to 50 mg/day.
| info =
* Duloxetine slows the metabolism of doxepin by CYP2D6.
* Caution is necessary at the start of administration of doxepin. }}
| from = duloxetine
| to = doxepin
| stop =
* '''Day 0:''' gradually reduce dosage of duloxetine to a maximum of 60 mg/ day, when this dosage is > 60 mg/day.
* '''Day 1:''' reduce dosage of duloxetine to a maximum of 30 mg/day.
| start =
A wash-out period of one week is necessary.
* '''Day 1:''' simultaneously start administration of doxepin in a low dosage of 25 mg/day.
* Day 8:''' stop administration of duloxetine and increase the dosage of doxepin to 50 mg/day.
| info =
* Duloxetine slows the metabolism of doxepin by CYP2D6.
* Caution is necessary at the start of administration of doxepin. }}