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A wash-out period of one week is necessary.
* '''Day 1:''' simultaneously start administration of doxepin in a low dosage of 25 mg/day.
* '''Day 8:''' stop administration of duloxetine and increase the dosage of doxepin to 50 mg/day.
| info =
* Duloxetine slows the metabolism of doxepin by CYP2D6.
* Caution is necessary at the start of administration of doxepin. }}
