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| start =
* ''' Day 2: ''' Start administration of fluvoxamine the next day in a normal dosage of 50 mg/day.
* ''' After 3 weeks: ''' If necessary, increase dosage of fluvoxamine gradually to 100-300 mg/day
| info =
* Fluvoxamine stops the metabolism of agomelatine via CYP1A2 and CYP2C9.
* A Wash-out period of one day is necessary
}}
