* '''Before day 1:''' gradually reduce dosage of clomipramine to a maximum of 75 mg/ day, when this dosage is > 75 mg/day.* '''Day 1-3:''' reduce dosage of clomipramine to 50 mg/day.* '''Day 4-7:''' reduce dosage of clomipramine to 25 mg/day.{{TCAdecrease25p3d}}* '''Day 8:''' stop administration of clomipramine. Stop and wait 10 days for washout

* '''Day 8-21:''' a wash-out period of two weeks 10 days is necessary.* '''Day 22-30:''' start administration of tranylcypromine in a low dosage of 20 mg/day for one week.* '''Day 31:''' after this week the dosage of tranylcypromine can be increased if necessary.{{Starttranyl}}