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Imipramine-fluvoxamine

398 bytes removed, 20 February
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* '''Before day 1:''' gradually reduce dosage of imipramine to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of imipramine to 50 mg/day.* '''Day 3:''' reduce dosage of imipramine to 25 mg/day.{{TCAdecrease25p3d}}
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* '''Day 4:''' simultaneously start administration of fluvoxamine in a normal dosage of 50 mg/day.* '''Day 8:''' stop administration of imipramine and continue administration of fluvoxamine in a dosage of 50-100 mg/day.{{StartfluvoxIA}}
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* Occurrence Fluvoxamine is an inhibitor of serotonin syndrome is theoretically possibleCYP2C19, so caution is necessarywhich metabolize imipramine.}}