Difference between revisions of "Citalopram-nortriptyline"
From Psychiatrienet
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| − | * ''' | + | * '''Before day 1:''' gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day. |
* '''Day 1:''' reduce dosage of citalopram/escitalopram to a maximum of 10 mg/day resp. 5 mg/day. | * '''Day 1:''' reduce dosage of citalopram/escitalopram to a maximum of 10 mg/day resp. 5 mg/day. | ||
| start = | | start = | ||
Revision as of 15:15, 11 September 2009
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Switch medication from citalopram to nortriptyline.[1] [2]
Stop citalopram - Before day 1: gradually reduce dosage of citalopram/escitalopram to a maximum of 20 mg/day resp. 10 mg/day, when this dosage is respectively > 20 mg/day and > 10 mg/day.
- Day 1: reduce dosage of citalopram/escitalopram to a maximum of 10 mg/day resp. 5 mg/day.
Start nortriptyline- Day 1: simultaneously start administration of nortriptyline in a normal dosage of 50 mg/day.
- Day 8: stop administration of citalopram/escitalopram and continue administration of nortriptyline only.
More information- “Start low, go slow” for nortriptyline is not required, but caution is necessary.
- The same applies to escitalopram.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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