Combining-Aripiprazole-Gabapentin

Ariprazole Type Antipsychotic Group Atypical AP Other use moodstabilizer links EMEA abilify PubChem 60975 PubMed Ariprazole Kompas (Dutch) Ariprazole Wikipedia Ariprazole more info

Gabapentin Type moodstabilizer Group anticonvulsant links ATC-code N03AX12 PubChem 3446 PubMed Gabapentin Drugs.com gabapentin Kompas (Dutch) Gabapentin Wikipedia Gabapentin more info T1/2 5-7h bioavailability 60% administration O

Adding gabapentin to aripiprazole.

General information

• Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
• Gabapentin is eliminated unchanged by the kidney for 100%.
• Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
• This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects.

Start gabapentin

• Start gabapentin according to the general dosing advice.

Cave

• Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects.

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