Combining-Ziprasidone-Aripiprazole

Ariprazole Type Antipsychotic Group Atypical AP Other use moodstabilizer links EMEA abilify PubChem 60975 PubMed Ariprazole Kompas (Dutch) Ariprazole Wikipedia Ariprazole more info

Ziprasidone Type Antipsychotic Group Atypical AP Other use Moodstabilizer links Medscape Ziprasidone PubChem 60854 PubMed Ziprasidone Wikipedia Ziprasidone more info

Adding ziprasidone to aripiprazole.

General information

• Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
• Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
• Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
• Ziprasidone is metabolized by CYP3A4 and CYP1A2 (minor).
• This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects.

Start ziprasidone

• Start ziprasidone according to the general dosing advice.

Cave

• Agents with anticholinergic properties may have additive effects when used in combination.

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