Difference between revisions of "Combining-Ziprasidone-Lithium"
From Psychiatrienet
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* Start lithium according to the general dosing advice. | * Start lithium according to the general dosing advice. | ||
Revision as of 13:22, 15 June 2010
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Adding lithium to Ziprasidone.
General information- Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
- Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
- Ziprasidone is metabolized by CYP3A4 and CYP1A2 (minor).
Start lithium- Start lithium according to the general dosing advice.
Cave- The concomitant administration of lithium with neuroleptic agents may increase the risk of extrapyramidal reactions and neurotoxicity.
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