Difference between revisions of "Amitriptyline-citalopram"

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| to = citalopram  
 
| to = citalopram  
 
| stop =  
 
| stop =  
* '''Before day 1:''' gradually reduce dosage of amitriptyline to a maximum of 50 mg/day.
+
{{TCAdecrease25p3d}}
* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.
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| start = {{StartAntidepressant}}
* '''Day 8:''' stop administration of amitriptyline.
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| info =
| start =  
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* Safe target dose citalopram = 20 mg
* '''Day 8:''' start administration of citalopram/escitalopram in a normal dosage of 20 mg/day, resp. 10 mg/day.
 
* '''Day 15:''' if necessary, increase dosage of citalopram/escitalopram.
 
| info =  
 
* {{theorSS}}
 
 
}}
 
}}

Latest revision as of 10:53, 30 June 2023

Amitriptyline
Type Antidepressant
Group TCA
links
ATC-code N06AA09
Medscape Amitriptyline
PubChem 2160
PubMed Amitriptyline
Kompas (Dutch) Amitriptyline
Wikipedia Amitriptyline
Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram

Switch medication from amitriptyline to citalopram.[1] [2]

Nietinrijdenbord.png Stop amitriptyline
  • Day 1: Decrease with about 25% of the original dose per 3 days.
Eenrichtingbord.png Start citalopram
  • Day 1: Start with 50% of the target dose
  • Day 8: Increase dose to 100% of the target dose
  • Day 9 and after: Gradually increase dose as necessary
Infobord.png More information
  • Safe target dose citalopram = 20 mg
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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