Difference between revisions of "Mianserine-mirtazapine"
From Psychiatrienet
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| to = mirtazapine | | to = mirtazapine | ||
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− | * ''' | + | * '''Before day 1:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day. |
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day. | * '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day. | ||
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* '''Day 8:''' stop administration of mianserine and only continue administration of mirtazapine in a dosage of 30 mg/day. | * '''Day 8:''' stop administration of mianserine and only continue administration of mirtazapine in a dosage of 30 mg/day. | ||
| info = | | info = | ||
− | * Mirtazapine and mianserine do have a quite identical pharmacological profile.}} | + | * Mirtazapine and mianserine do have a quite identical antidepressive pharmacological profile.}} |
Latest revision as of 15:11, 17 November 2009
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Switch medication from mianserine to mirtazapine.[1] [2]
- Before day 1: gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
- Day 1: reduce a dosage of 60 mg/day to 30 mg/day.
- Day 1: simultaneously start mirtazapine in a low dosage of 15 mg/day.
- Day 8: stop administration of mianserine and only continue administration of mirtazapine in a dosage of 30 mg/day.
- Mirtazapine and mianserine do have a quite identical antidepressive pharmacological profile.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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