Difference between revisions of "Mianserine-venlafaxine"
From Psychiatrienet
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| to = venlafaxine | | to = venlafaxine | ||
| stop = | | stop = | ||
| − | * ''' | + | * '''Before day 1:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day. |
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day. | * '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day. | ||
| + | * '''Day 8:''' stop administration of mianserine. | ||
| start = | | start = | ||
| − | * '''Day 1:''' | + | * '''Day 1:''' Simultaneously {{startVenla}} |
| − | * '''Day 8:''' | + | * '''Day 8:''' Continue administration of venlafaxine. If necessary, increase the dosage of venlafaxine. |
| − | |||
| caveat = | | caveat = | ||
* Occurrence of serotonin syndrome is (not very likely) possible, so caution is necessary.}} | * Occurrence of serotonin syndrome is (not very likely) possible, so caution is necessary.}} | ||
Latest revision as of 16:25, 27 November 2009
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Switch medication from mianserine to venlafaxine.[1] [2]
Stop mianserine - Before day 1: gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
- Day 1: reduce a dosage of 60 mg/day to 30 mg/day.
- Day 8: stop administration of mianserine.
Start venlafaxine- Day 1: Simultaneously Start administration of venlafaxine in a normal dosage of 37,5 mg or 75 mg (slow release) /day.
- Day 8: Continue administration of venlafaxine. If necessary, increase the dosage of venlafaxine.
Cave- Occurrence of serotonin syndrome is (not very likely) possible, so caution is necessary.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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