Difference between revisions of "Combining-Gabapentin-Topiramate"
From Psychiatrienet
(Created page with '{{Drugcombi | base = gabapentin | add = topiramate | info = * Gabapentine is eliminated unchanged by the kidney for 100%. Changes in the rate of excretion can cause unwanted eff...') |
|||
| (4 intermediate revisions by the same user not shown) | |||
| Line 3: | Line 3: | ||
| add = topiramate | | add = topiramate | ||
| info = | | info = | ||
| − | * | + | *{{CombiNoInteraction}} |
| − | |||
| − | |||
| start = | | start = | ||
* Start topiramate according to the general dosing advice. | * Start topiramate according to the general dosing advice. | ||
| cave = | | cave = | ||
}} | }} | ||
Latest revision as of 15:18, 21 April 2010
| ||||||||||||||||||||||||||||||
| ||||||||||||||||||||||||||||||
Adding topiramate to gabapentin.
General information- Gabapentin is eliminated unchanged by the kidney for 100%.
- Topiramate induces CYP3A4 and is an inhibitor of CYP2C19.
- This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. [2]
Start topiramate- Start topiramate according to the general dosing advice.
- ↑ 1.0 1.1 1.2 Farmacotherapeutisch Kompas - gabapentine (dutch)
Cite error: Invalid
<ref>tag; name "ftk" defined multiple times with different content Cite error: Invalid<ref>tag; name "ftk" defined multiple times with different content - ↑ Freeman et al. Mood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.
