Difference between revisions of "Combining-Lithium-Aripiprazole"
From Psychiatrienet
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| − | * This combination may have additive side effects<ref name= </ref>. | + | * This combination may have additive side effects<ref name= ="drugscom"> |
| + | {{Drugscominteract|aripiprazole-with-lithium-233-0-1477-0|aripiprazole|lithium}}</ref>. | ||
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Latest revision as of 21:06, 6 June 2010
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Adding aripiprazole to lithium.
General information- Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
- Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
- This combination may have additive side effects[2].
Start aripiprazole- Start aripiprazole according to the general dosing advice.
Cave- The concomitant administration of lithium with neuroleptic agents may increase the risk of extrapyramidal reactions and neurotoxicity.
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