Difference between revisions of "Mianserine-fluvoxamine"
From Psychiatrienet
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| to = fluvoxamine | | to = fluvoxamine | ||
| stop = | | stop = | ||
| − | * ''' | + | * '''Before day 1:''' gradually reduce dosage of mianserine to a maximum of 60 mg/ day. |
* '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day. | * '''Day 1:''' reduce a dosage of 60 mg/day to 30 mg/day. | ||
| start = | | start = | ||
* '''Day 1:''' simultaneously start fluvoxamine in a normal dosage of 50 mg/day. | * '''Day 1:''' simultaneously start fluvoxamine in a normal dosage of 50 mg/day. | ||
| − | * '''Day 8:''' stop administration of mianserine and only continue administration of fluvoxamine | + | * '''Day 8:''' stop administration of mianserine and only continue administration of fluvoxamine. |
* If necessary, increase the dosage of fluvoxamine. | * If necessary, increase the dosage of fluvoxamine. | ||
}} | }} | ||
Latest revision as of 15:10, 17 November 2009
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Switch medication from mianserine to fluvoxamine.[1] [2]
Stop mianserine - Before day 1: gradually reduce dosage of mianserine to a maximum of 60 mg/ day.
- Day 1: reduce a dosage of 60 mg/day to 30 mg/day.
Start fluvoxamine- Day 1: simultaneously start fluvoxamine in a normal dosage of 50 mg/day.
- Day 8: stop administration of mianserine and only continue administration of fluvoxamine.
- If necessary, increase the dosage of fluvoxamine.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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