SwitchAntipsychotics

Switching Antipsychotics (part of www.psychiatrienet.nl)

To see the consequences of a switch between antipsychotics click in the crosstable below: the switch is made "from" (vertical) "to" (horizontal).
During switching: don't reduce anticholinergics; consider adding oxazepam. Read: General considerations concerning switching antipsychotics.

Rest AP = Chlorprothixene, Flupentixol, Loxapine, Paliperidone, Pericyazine, Perphenazine,Promazine, Trifluoperazine, Zuclopentixol.

Partial antagonist new = Aripiprazole, Brexpiprazole, Cariprazine.

↓ from	to →	Am	Cp	Hp	Lu	Ol	Pa	Pi	Qu	Rd	Sd	Sr	Zi	RA	Da	Df	Di	Dh	Do	Dp	Dr	Dz	Mz	{{{afk23}}}
Am	Amisulpride	—	AmCp	AmHp	AmLu	AmOl	AmPa	AmPi	AmQu	AmRd	AmSd	AmSr	AmZi	AmRA	AmDa	—	—	—	—	—	—	—	—	[[Amisulpride-{{{med23}}}|Am{{{afk23}}}]]
Cp	Clozapine	CpAm	—	CpHp	CpLu	CpOl	CpPa	CpPi	CpQu	CpRd	CpSd	CpSr	CpZi	CpRA	CpDa	—	—	—	—	—	—	—	—	[[Clozapine-{{{med23}}}|Cp{{{afk23}}}]]
Hp	Haloperidol	HpAm	HpCp	—	HpLu	HpOl	HpPa	HpPi	HpQu	HpRd	HpSd	HpSr	HpZi	HpRA	HpDa	—	—	—	HpDo	—	—	—	—	[[Haloperidol-{{{med23}}}|Hp{{{afk23}}}]]
Lu	Lurasidone	LuAm	LuCp	LuHp	—	LuOl	LuPa	LuPi	LuQu	LuRd	LuSd	LuSr	LuZi	LuRA	LuDa	—	—	—	—	—	—	—	—	[[Lurasidone-{{{med23}}}|Lu{{{afk23}}}]]
Ol	Olanzapine	OlAm	OlCp	OlHp	OlLu	—	OlPa	OlPi	OlQu	OlRd	OlSd	OlSr	OlZi	OlRA	OlDa	—	—	—	—	OlDp	—	—	—	[[Olanzapine-{{{med23}}}|Ol{{{afk23}}}]]
Pa	Partial agonist	PaAm	PaCp	PaHp	PaLu	PaOl	—	PaPi	PaQu	PaRd	PaSd	PaSr	PaZi	PaRA	PaDa	—	—	—	—	—	PaDr	PaDz	—	[[Partial agonist-{{{med23}}}|Pa{{{afk23}}}]]
Pi	Pimozide	PiAm	PiCp	PiHp	PiLu	PiOl	PiPa	PiPi	PiQu	PiRd	PiSd	PiSr	PiZi	PiRA	PiDa	PiDf	—	—	—	—	—	—	—	[[Pimozide-{{{med23}}}|Pi{{{afk23}}}]]
Qu	Quetiapine	QuAm	QuCp	QuHp	QuLu	QuOl	QuPa	QuPi	—	QuRd	QuSd	QuSr	QuZi	QuRA	QuDa	—	—	—	—	—	—	—	—	[[Quetiapine-{{{med23}}}|Qu{{{afk23}}}]]
Rd	Risperidone	RdAm	RdCp	RdHp	RdLu	RdOl	RdPa	RdPi	RdQu	—	RdSd	RdSr	RdZi	RdRA	RdDa	—	—	—	—	—	—	—	—	[[Risperidone-{{{med23}}}|Rd{{{afk23}}}]]
Sd	Sertindole	SdAm	SdCp	SdHp	SdLu	SdOl	SdPa	SdPi	SdQu	SdRd	—	SdSr	SdZi	SdRA	SdDa	—	—	—	—	—	—	—	—	[[Sertindole-{{{med23}}}|Sd{{{afk23}}}]]
Sr	Sulpiride	SrAm	SrCp	SrHp	SrLu	SrOl	SrPa	SrPi	SrQu	SrRd	SrSd	—	SrZi	SrRA	SrDa	—	—	—	—	—	SrDr	SrDz	—	[[Sulpiride-{{{med23}}}|Sr{{{afk23}}}]]
Zi	Ziprasidone	ZiAm	ZiCp	ZiHp	ZiLu	ZiOl	ZiPa	ZiPi	ZiQu	ZiRd	ZiSd	ZiSr	—	ZiRA	ZiDa	—	—	—	—	—	—	—	—	[[Ziprasidone-{{{med23}}}|Zi{{{afk23}}}]]
RA	Rest AP	RAAm	RACp	RAHp	RALu	RAOl	RAPa	RAPi	RAQu	RARd	RASd	RASr	RAZi	—	RADa	—	—	—	—	—	—	—	—	[[Rest AP-{{{med23}}}|RA{{{afk23}}}]]
Da	Aripiprazole_LA	DaAm	DaCp	DaHp	DaLu	DaOl	DaPa	DaPi	DaQu	DaRd	DaSd	DaSr	DaZi	DaRA	DaDa	—	DaDi	DaDh	—	—	—	—	DaMz	[[Aripiprazole_LA-{{{med23}}}|Da{{{afk23}}}]]
Df	Fluphenazine_LA	DfAm	DfCp	DfHp	DfLu	DfOl	DfPa	DfPi	DfQu	DfRd	DfSd	DfSr	DfZi	DfRA	DfDa	—	—	—	—	—	—	—	—	[[Fluphenazine_LA-{{{med23}}}|Df{{{afk23}}}]]
Di	Flupenthixol_LA	DiAm	DiCp	DiHp	DiLu	DiOl	DiPa	DiPi	DiQu	DiRd	DiSd	DiSr	DiZi	DiRA	DiDa	—	—	—	—	—	—	—	—	[[Flupenthixol_LA-{{{med23}}}|Di{{{afk23}}}]]
Dh	Haloperidol_LA	DhAm	DhCp	DhHp	DhLu	DhOl	DhPa	DhPi	DhQu	DhRd	DhSd	DhSr	DhZi	DhRA	DhDa	—	—	—	—	—	—	—	—	[[Haloperidol_LA-{{{med23}}}|Dh{{{afk23}}}]]
Do	Olanzapine_LA	DoAm	DoCp	DoHp	DoLu	DoOl	DoPa	DoPi	DoQu	DoRd	DoSd	DoSr	DoZi	DoRA	DoDa	—	—	—	—	—	—	—	—	[[Olanzapine_LA-{{{med23}}}|Do{{{afk23}}}]]
Dp	Paliperidone_LA	DpAm	DpCp	DpHp	DpLu	DpOl	DpPa	DpPi	DpQu	DpRd	DpSd	DpSr	DpZi	DpRA	DpDa	—	—	—	—	—	—	—	—	[[Paliperidone_LA-{{{med23}}}|Dp{{{afk23}}}]]
Dr	Risperidone_LA	DrAm	DrCp	DrHp	DrLu	DrOl	DrPa	DrPi	DrQu	DrRd	DrSd	DrSr	DrZi	DrRA	DrDa	—	—	—	—	—	DrDr	DrDz	—	[[Risperidone_LA-{{{med23}}}|Dr{{{afk23}}}]]
Dz	Zuclopenthixol_LA	DzAm	DzCp	DzHp	DzLu	DzOl	DzPa	DzPi	DzQu	DzRd	DzSd	DzSr	DzZi	DzRA	DzDa	—	—	—	—	—	DzDr	—	—	[[Zuclopenthixol_LA-{{{med23}}}|Dz{{{afk23}}}]]
Mz	Zuclopenthixol_MA	MzAm	MzCp	MzHp	MzLu	MzOl	MzPa	MzPi	MzQu	MzRd	MzSd	MzSr	MzZi	MzRA	MzDa	—	—	—	—	—	—	—	—	[[Zuclopenthixol_MA-{{{med23}}}|Mz{{{afk23}}}]]
{{{afk23}}}		[[{{{med23}}}-Amisulpride|{{{afk23}}}Am]]	[[{{{med23}}}-Clozapine|{{{afk23}}}Cp]]	[[{{{med23}}}-Haloperidol|{{{afk23}}}Hp]]	[[{{{med23}}}-Lurasidone|{{{afk23}}}Lu]]	[[{{{med23}}}-Olanzapine|{{{afk23}}}Ol]]	[[{{{med23}}}-Partial agonist|{{{afk23}}}Pa]]	[[{{{med23}}}-Pimozide|{{{afk23}}}Pi]]	[[{{{med23}}}-Quetiapine|{{{afk23}}}Qu]]	[[{{{med23}}}-Risperidone|{{{afk23}}}Rd]]	[[{{{med23}}}-Sertindole|{{{afk23}}}Sd]]	[[{{{med23}}}-Sulpiride|{{{afk23}}}Sr]]	[[{{{med23}}}-Ziprasidone|{{{afk23}}}Zi]]	[[{{{med23}}}-Rest AP|{{{afk23}}}RA]]	[[{{{med23}}}-Aripiprazole_LA|{{{afk23}}}Da]]	—	—	—	—	—	—	—	[[{{{med23}}}-Zuclopenthixol_MA|{{{afk23}}}Mz]]	—

LA = long acting, MA = medium acting

(part of www.psychiatrienet.nl)