Difference between revisions of "Mirtazapine-clomipramine"
From Psychiatrienet
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* '''Day 1:''' simultaneously start administration of clomipramine in a dosage of 75 mg/day. | * '''Day 1:''' simultaneously start administration of clomipramine in a dosage of 75 mg/day. | ||
* '''Day 8:''' stop administration of mirtazapine and continue administration of clomipramine. If necessary, increase dosage of clomipramine. | * '''Day 8:''' stop administration of mirtazapine and continue administration of clomipramine. If necessary, increase dosage of clomipramine. | ||
| − | * Start low, go slow.}} | + | * Start low, go slow. |
| + | | info = | ||
| + | {{review}} | ||
| + | }} | ||
Revision as of 14:14, 7 October 2015
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Switch medication from mirtazapine to clomipramine.[1] [2]
Stop mirtazapine - Before day 1: gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.
- Day 1: reduce a dosage of 30 mg/day to 15 mg/day.
Start clomipramineNo wash-out period is needed.
- Day 1: simultaneously start administration of clomipramine in a dosage of 75 mg/day.
- Day 8: stop administration of mirtazapine and continue administration of clomipramine. If necessary, increase dosage of clomipramine.
- Start low, go slow.
More information- This switch is currently being reviewed.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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