Difference between revisions of "Agomelatine-clomipramine"

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* '''Day 2: ''' Start administration of clomipramine in a normal dosage of 50-75 mg/day.
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* A wash-out period is not necessary.
 
* A wash-out period is not necessary.
* Start administration of clomipramine the next day in a normal dosage of 50-75 mg/day.
 
 
 
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Revision as of 10:54, 14 October 2015

Agomelatine
Type Antidepressant
Group other
links
ATC-code N06AX22
EMEA valdoxan
PubChem 82148
PubMed Agomelatine
Kompas (Dutch) Agomelatine
Wikipedia Agomelatine
Clomipramine
Type Antidepressant
Group TCA
links
ATC-code N06AA04
Medscape Clomipramine
PubChem 2801
PubMed Clomipramine
Kompas (Dutch) Clomipramine
Wikipedia Clomipramine

Switch medication from agomelatine to clomipramine.[1] [2]

Nietinrijdenbord.png Stop agomelatine
  • Day 1: Stop agomelatine.
  • Agomelatine can be stopped abruptly for every dosage.[3]
Eenrichtingbord.png Start clomipramine
  • Day 2: Start administration of clomipramine in a normal dosage of 50-75 mg/day.
Infobord.png More information
  • A wash-out period is not necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. McAllister-Williams RH et al. The use of antidepressants in clinical practice: focus on agomelatine. Hum Psychopharmacol. 2010 Mar 1;25(2):95-102
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