Combining-Carbamazepine-Gabapentin
From Psychiatrienet
{{Drugcombi | base = carbamazepine | add = gabapentin | info =
- Carbamazepine is principally metabolized by CYP3A4 (also CYP2C8), but is also a potent inducer of CYP1A2, CYP3A4 and UDP-glucuronosyltransferases.
- Gabapentine is eliminated unchanged by the kidney for 100%.
- {{CombiNoInteraction}
| start =
- Start gabapentine according to the general dosing advice.
| cave =
- Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects. [1]
}}
