Vortioxetine-amitriptyline

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{{ Drugswitch | from = vortioxetine | to = amitriptyline | stop =

  • Day 1: stop administration of vortioxetine.

| start = No wash-out period is needed.

  • Day 1: simultaneously start administration of amitriptyline in a dosage of 25 mg/day.
  • Day 8: continue administration of amitriptyline in a dosage of 50 mg/day.
  • Start low, go slow.