Combining-Lithium-Quetiapine
From Psychiatrienet
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Adding quetiapine to lithium.
General information- Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
- Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
- Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
- Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
- This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
Start quetiapine- Start quetiapine according to the general dosing advice.
- ↑ Farmacotherapeutisch Kompas - lithium (dutch)
- ↑ 2.0 2.1 2.2 KNMP; Informatorium Medicamentorum 2023; Monografie "quetiapine" (Dutch)
- ↑ NVZA; Toxicology.org; Monografie 73 (dutch)
- ↑ Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics J Clin Psychiatry 2003;64:663-667
- ↑ Drugs.com quetiapine-fumarate
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