Combining-Gabapentin-Aripiprazole

Gabapentin Type moodstabilizer Group anticonvulsant links ATC-code N03AX12 PubChem 3446 PubMed Gabapentin Drugs.com gabapentin Kompas (Dutch) Gabapentin Wikipedia Gabapentin more info T1/2 5-7h bioavailability 60% administration O

Ariprazole Type Antipsychotic Group Atypical AP Other use moodstabilizer links EMEA abilify PubChem 60975 PubMed Ariprazole Kompas (Dutch) Ariprazole Wikipedia Ariprazole more info

Adding aripiprazole to gabapentin.

General information

• Gabapentin is eliminated unchanged by the kidney for 100%.
• Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
• Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
• This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects.

Start aripiprazole

• Start aripiprazole according to the general dosing advice.

Cave

• Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects.

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