Stop-trazodone

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Trazodone
Type Antidepressant
Group other
links
Medscape Trazodone
PubChem 5533
PubMed Trazodone
Kompas (Dutch) Trazodone
Wikipedia Trazodone


Nietinrijdenbord.png Stop trazodone
  • In general after long-term maintenance treatment, the best is to reduce the dose by about 25% every 4-6 weeks. An apt pharmaceutical dose (tablet, capsule, mixture) is not always available. In these cases one should be creative with dosing.[1][2]
  • Another, more risky, possibility is being at a certain dose to use the following scheme:
  • 400 mg/day:
  • Day 1: reduce dosage of trazodone to 300 mg/day.
  • Day 8: reduce dosage of trazodone to 200 mg/day.
  • Day 15: reduce dosage of trazodone to 100 mg/day.
  • Day 22: reduce dosage of trazodone to 50 mg/day.
  • Day 29: stop administration of trazodone.



  1. The UK Drug and Therapeutics Bulletin; 1999;37:49-52
  2. Editor: please note that not all dosages are available in pharmacy. So now and then you should be creative.
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