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Combining-Lamotrigine-Topiramate

491 bytes added, 15:25, 4 March 2010
Created page with '{{Drugcombi | base = Lamotrigine | add = Topiramate | info = * Lamoptrigine is principally metabolised by UDP-glucuronosyltransferases. * Topiramate induces CYP3A4 and is an inh...'
{{Drugcombi
| base = Lamotrigine
| add = Topiramate
| info =
* Lamoptrigine is principally metabolised by UDP-glucuronosyltransferases.
* Topiramate induces CYP3A4 and is an inhibiter of CYP2C19.
| start =
* Topiramate does not cause a significant change in lamotrigine levels. Start topiramate according to the general dosing advice. <ref> {{Pubmed|12180999|Berry at al, Lack of an effect of topiramate on lamotrigine serum concentrations. Epilepsia 2002;43(8):818-23}}</ref>
| cave =
}}
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