| base = Lamotriginelamotrigine| add = Topiramatetopiramate
| info =
* Lamoptrigine is principally metabolised by UDP-glucuronosyltransferases.
* Topiramate induces CYP3A4 and is an inhibiter inhibitor of CYP2C19.
| start =
* Topiramate does not cause a significant change in lamotrigine levels. Start topiramate according to the general dosing advice. <ref> {{Pubmed|12180999|Berry at al, Lack of an effect of topiramate on lamotrigine serum concentrations. Epilepsia 2002;43(8):818-23}}</ref>