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Venlafaxine-maprotiline

401 bytes removed, 17:16, 17 July 2009
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| to = maprotiline
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* '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.* '''Day 1:''' reduce a dosage of 75 mg/day to 37,5 mg/day.{{downVenla}}
| start =
* '''Day 115:''' simultaneously start administration of maprotiline in a low dosage of 25-75 mg/day.* '''Day 8:''' stop administration of venlafaxine and continue administration of maprotiline.
| info =
* “Start low, go slow” is not required, but caution with this switch is necessary. * Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes maprotiline.}}
Walter
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