838
edits
Changes
Created page with '{{Drugswitch | from = venlafaxine | to = maprotiline | stop = * '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day. * '''Day 1:''' reduce a dosage o...'
{{Drugswitch
| from = venlafaxine
| to = maprotiline
| stop =
* '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.
* '''Day 1:''' reduce a dosage of 75 mg/day to 37,5 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of maprotiline in a low dosage of 25-75 mg/day.
* '''Day 8:''' stop administration of venlafaxine and continue administration of maprotiline.
| info =
* “Start low, go slow” is not required, but caution with this switch is necessary.
* Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes maprotiline.}}
| from = venlafaxine
| to = maprotiline
| stop =
* '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.
* '''Day 1:''' reduce a dosage of 75 mg/day to 37,5 mg/day.
| start =
* '''Day 1:''' simultaneously start administration of maprotiline in a low dosage of 25-75 mg/day.
* '''Day 8:''' stop administration of venlafaxine and continue administration of maprotiline.
| info =
* “Start low, go slow” is not required, but caution with this switch is necessary.
* Venlafaxine is a weak inhibitor of CYP2D6, which metabolizes maprotiline.}}
