Combining-Quetiapine-Lithium

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Quetiapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH04
Medscape Quetiapine
PubChem 5002
PubMed Quetiapine
Drugs.com quetiapine-fumarate
Kompas (Dutch) Quetiapine
Wikipedia Quetiapine
Lithium
Type moodstabilizer
Group other
links
ATC-code N05AN01
Medscape Lithium
PubChem 11125
PubMed Lithium
Drugs.com lithium
Kompas (Dutch) Lithium
Wikipedia Lithium

Adding lithium to quetiapine.

Infobord.png General information
  • Quetiapine is principally metabolized by CYP3A4 to active and inactive metabolites.
  • Lithium is eliminated by the kidney for about 95%. Changes in the rate of excretion can cause unwanted effects.
  • This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination. [6]
Eenrichtingbord.png Start lithium
  • Start lithium according to the general dosing advice.
Letopbord.png Cave
  • During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. [7]


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