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{{TCAdecrease25p3d}}
| start =
* '''Day 6 7 and after''': At approximately 50-25% of the original venlafaxine dose start fluoxetine at 100% of the target dose.
* ''' After 3 weeks:''' If necessary, gradually increase dosage of fluoxetine.
| info =
* Safe target dose fluoxetine = 20 mg
* Fluoxetine and norfluoxetine are inhibitors of CYP2D6 (strong), which metabolizes venlafaxine. It prolongs the halftime of venlafaxine which decreases the chances of withdrawal
}}
