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* '''Day 1:''' reduce dosage of doxepin to 50 mg/day.
* '''Day 8:''' reduce dosage of doxepin to 25 mg/day.
* '''Day 15:''' stop administration of doxepin.
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* '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.
* '''Day 15:''' stop administration of doxepin and only continue administration of agomelatine.* If necessary, increase dosage of agomelatine to 50 mg/day. }}
