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| to = agomelatine
| stop =
* '''Before day 0:''' gradually reduce dosage of sertraline to a maximum of 50 100 mg/day, when this dosage is > 100 mg/day. * '''Day 1:''' reduce dosage of sertraline to 50 mg/day. * '''Day 18:''' reduce dosage of sertraline to 25 mg/day.* '''Day 815:''' stop administration of sertraline.
| start =
* '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.
* '''Day 815:''' only continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day. }}
