Changes

| to = nortriptylinecitalopram

* '''Day 0:''' gradually Gradually reduce dosage of sertraline to a maximum of 50 mg/day , when this dosage is > 50 mg/day. * '''Day 1:''' reduce When a dosage of sertraline to a maximum of 25 50 mg/dayis reached, stop administration.

Caution * No wash-out period is necessaryneeded.* '''Day 1:''' simultaneously start administration of nortriptyline in a low dosage of 25 mg/Start sertraline the next day. * '''Day 8:''' stop administration of sertraline and only continue administration of nortriptyline in a normal dosage of 50 mg/day.* "Start low, go slow" is not required, but caution is necessary.| info = * Sertraline dose-dependently slows the metabolism of amitriptyline via CYP2D6. }}