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* A wash-out period is not necessary.
* '''Day 1:''' simultaneously start administration of citalopram/escitalopram in a normal dosage of 20 mg/day, resp. 10 mg/day.* '''Day 8:''' stop administration of trazodone and continue administration of citalopram/escitalopram.
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* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* Citalopram/escitalopram are a weak inhibitor of CYP2D6, which metabolizes tranzodonetrazodone. }}