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Created page with '{{ Drugswitch | from = trazodone | to = bupropion | stop = * '''Before day 0:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/...'
{{ Drugswitch
| from = trazodone
| to = bupropion
| stop =
* '''Before day 0:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day.
* '''Day 1:''' reduce dosage of trazodone to 75 mg/day.
* '''Day 8:''' stop administration of trazodone.
| start =
* A wash-out period is not necessary.
* '''Day 8:''' simultaneously start administration of bupropion in a normal dosage of 150 mg/day.
* '''Day 15:''' increase dosage of bupropion to 300 mg/day.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes trazodone.}}
| from = trazodone
| to = bupropion
| stop =
* '''Before day 0:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day, when this dosage is > 150 mg/day.
* '''Day 1:''' reduce dosage of trazodone to 75 mg/day.
* '''Day 8:''' stop administration of trazodone.
| start =
* A wash-out period is not necessary.
* '''Day 8:''' simultaneously start administration of bupropion in a normal dosage of 150 mg/day.
* '''Day 15:''' increase dosage of bupropion to 300 mg/day.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes trazodone.}}
