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| start =
* A wash-out period is not necessary, but care is needed.
* '''Day 8:''' simultaneously start administration of bupropion in a normal dosage of 150 mg/day.
* '''Day 15:''' increase dosage of bupropion to 300 mg/day.
| info =
* Bupropion is a strong inhibitor of CYP2D6, which metabolizes trazodone.}}
